- Obstetricians & Gynecologists, Martinsburg - Ob-Gyn Doctors, Physicians & Surgeons (Obstetrics & Gynecology)
- Off Road Vehicles, Martinsburg
- Off Road Vehicles Parts & Accessories, Martinsburg
- Office Supplies, Equipment & Office Furniture Stores, Martinsburg
- Oil Change & Lubrication, Martinsburg - Auto Oil & Quick Lube
- Oncologists, Martinsburg - Cancer Doctors, Physicians & Surgeons (Oncology)
- Ophthalmologists, Martinsburg - Eye Doctors, Physicians & Surgeons (Ophthalmology)
- Optical Goods Manufacturers, Martinsburg
- Optical Stores - Eyeglasses, Lenses & Sunglasses, Martinsburg
- Opticians, Martinsburg
- Optometrists, Martinsburg - Eye Doctors, Physicians & Surgeons (Optometry)
- Oral Surgeon, Martinsburg - Dentists - Oral & Maxillofacial Surgeons
- Orchard Service, Martinsburg
- Ornamental Nursery, Martinsburg
- Ornamental Nursery Services, Martinsburg
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- Orthodontist, Martinsburg - Teeth Straightening, Invisalign & Dental Braces
- Orthopedic & Prosthetic Appliances & Shoes, Martinsburg - Orthopedic Shoes
- Orthopedists, Martinsburg - Orthopedic Surgery Doctors, Physicians & Surgeons
- Orthotics and Prosthetics, Martinsburg
- Other Attorneys & Lawyers, Martinsburg
- Other Attorneys & Lawyers, Martinsburg
- Other Building Materials & Supplies, Martinsburg
- Other Lawyers & Attorneys, Martinsburg
- Other Office Supply Stores, Martinsburg
- Outdoor & Lawn & Garden Equipment Repair & Service, Martinsburg
- Outdoor Advertising & Billboard, Martinsburg
- Outdoor Equipment & Accessories, Martinsburg
- Outdoor Furniture & Patio Furniture, Martinsburg - Garden Furniture Stores
- Oxygen & Respiratory Equipment & Supplies, Martinsburg - Oxygen Concentrator, Tank, Machine, etc
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